Focus Features has released two new scenes from the upcoming Matthew McConaughey drama Dallas Buyers Club, about an HIV-positive electrician who works outside the system to get untested antiviral drugs in the hands of desperate patients like himself.  The film is based on the true story of Ron Woodroof, who created one of the first buyers' clubs when AZT was the only FDA- approved medication for people with HIV/AIDS.

Related: “Dallas Buyers Club” Trailer Is Here. Is This McConaughey’s Oscar Moment?

Above, Jared Leto plays Rayon, a transgender prostitute being examined by her doctor (Jennifer Gardner). At the Toronto International Film Festival, Leto said he felt “very connected" to the role. "I was in character [on set], which I know is a terrible term because it brings up ideas of pretentiousness. But how could you throw it all away, go have lunch, and then ‘action’?"

Below, an emaciated McConaughey (who lost more than 40lbs for the movie) faces federal agents questioning his methods.

Dallas Buyers Club opens in theaters November 1