Madonna knows her audience.

Hot on the cha cha heels of “Medellín,” the 60-year-old icon has released "I Rise," a powerful track from her upcoming 14th studio album, Madame X.

The seditious ballad, about summoning the strength to survive life's struggles, starts with a snippet from an impassioned speech by Parkland survivor and bisexual activist Emma González.

"I wrote ‘I Rise’ as a way of giving a voice to all marginalized people who feel they don’t have the opportunity to speak their mind," says Madonna in a statement. "This year is the 50th anniversary of Pride and I hope this song encourages all individuals to be who they are, to speak their minds and to love themselves."

It's rumored that the music video for “I Rise” will also be a love letter to the LGBTQ community, featuring drag queens like Monét X Change. And don't forget Madonna's surprise New Year’s Eve appearance at Stonewall Inn.

Madonna will be honored Saturday, May 4, with the Advocate for Change Award at the 30th Annual GLAAD Media Awards in New York City.

“I Rise” is the second of five songs being released to preview Madame X. Listen for “Crave,” “Future,” and “Dark Ballet” in the coming weeks.

Madonna and Maluma performed their new collaboration, “Medellín,” earlier this week at the 2019 Billboard Music Awards.

Madame X, out June 14, is now available for pre-order.