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Try Not To Cry During The Trailer For "Miss You Already," Starring Toni Collette And Drew Barrymore

The trailer for the movie Miss You Already has hit the interwebs, and it has us lunging for a tissue.

Related: Watch The First Trailer For Katherine Heigl’s Lesbian Wedding Drama Jenny’s Wedding

The movie, starring Toni Collette and Drew Barrymore, centers around Jess (Barrymore) and Milly (Collette)–two women living in London who've been best friends since childhood.

As Barrymore's voiceover explains, Milly–who was always the more rambunctious and free spirited of the duo–ended up becoming a mom of two, while the caustic Jess and her husband can't seem to get pregnant.

Things take a turn when Milly is diagnosed with breast cancer, just as Jess gets some good news in the baby department.

While their opposite fortunes collide, it looks like true friendship will prevail, in a Beaches/Muriel's Wedding sort of way.

Directed by Catherine Hardwicke (Thirteen, Twilight), the movie has all the right ingredients for a bonafide sobfest for you and your bestie.

Watch the trailer below.

Miss You Already hits theaters September 25.

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